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T-cell and NK-cell infiltration into solid tumors: a key limiting factor for efficacious cancer immunotherapy
Discover how tumors evade immune responses and limit cancer immunotherapy success. Explore strategies to enhance T-cell and NK-cell infiltration, overcome tumor immune barriers, and improve treatment efficacy.
Tumor blood vessels, a difficult hurdle for infiltrating leukocytes
Explore how tumors evade immune responses by suppressing endothelial adhesion molecules, limiting leukocyte recruitment. Learn about novel strategies to enhance immune cell infiltration and improve cancer immunotherapy outcomes.
Endothelial intercellular adhesion molecule-1 expression is suppressed in human malignancies: the role of angiogenic factors
Discover how angiogenic factors suppress ICAM-1 expression in tumors, limiting leukocyte infiltration and aiding immune evasion. Learn about the role of endothelial adhesion molecules in cancer progression and potential therapeutic strategies.